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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence as outlined by a news release by them on 10-12-2010.

Using two separate drugs to shed pounds can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the people that go through it you ought to err to the side of caution and permit the FDA do its job and demand some investigation be done in order that the public knows the side effects and risks of the medications before we bring them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on their medications.

Researchers discovered that participants taking this drug for the year, lost excess weight within four weeks and have kept the body weight off through the 56 weeks of the study. Contrave is a combination with the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which are made up of several active ingredient, which might make them far better and safer.

Combo-pilling may be the newest fad or even better the newest in the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular may be the fact that by right now there are no long term prescription weight loss supplements that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be approved by the FDA.

Seizures certainly are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug may also raise hypertension and heart rate, and shouldn't be used in those with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heart rate and must not be used in patients with uncontrolled high hypertension, along with by you are not heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients with a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients towards the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking.


The most common unwanted effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.
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